• Lecithin and Chitosan as Building Blocks in Anti-Candida Clotrimazole Nanoparticles 

      Hemmingsen, Lisa Myrseth; Panzacchi, Virginia; Kangu, Lloyd Mbugua; Giordani, Barbara; Luppi, Barbara; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-25)
      The main focus when considering treatment of non-healing and infected wounds is tied to the microbial, particularly bacterial, burden within the wound bed. However, as fungal contributions in these microbial communities become more recognized, the focus needs to be broadened, and the remaining participants in the complex wound microbiome need to be addressed in the development of new treatment ...
    • Novel in situ gel-forming solid dosage form (gfSDF) prepared by the simple syringe-based moulding: A screening study 

      Falavigna, Margherita; Skalko-Basnet, Natasa; Cavallari, Cristina; Pini, Andrea; Luppi, Barbara; Di Cagno, Massimiliano Pio (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-05)
      The aim of this study was to prepare and optimize a novel type of in situ gel-forming solid dosage form (gfSDF) to be used in the treatment of mucosal/skin ulcerations. For this purpose, a simple but reliable syringe-based hot melt/moulding method was employed. Chloramphenicol (antibiotic) and ibuprofen (anti-inflammatory) were chosen as model active pharmaceutical ingredients (APIs) to be loaded ...
    • Utilizing Liposomal Quercetin and Gallic Acid in Localized Treatment of Vaginal Candida Infections 

      Giordani, Barbara; Basnet, Purusotam; Mishchenko, Ekaterina; Luppi, Barbara; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-20)
      Vulvovaginal candidiasis (VVC) is a widely spread fungal infection that causes itching, pain and inflammation at the vaginal site. Although common, currently available treatment suffers from limited efficacy and high recurrence. In addition, the growing problem of resistance to azole drugs used in current treatments emphasizes the need for superior treatment options. Antimicrobial polyphenols are ...